The USC Trojans (2-0) and the Purdue Boilermakers (2-0) square off on Saturday, September 13, 2025 at Ross-Ade Stadium in a clash of Big Ten opponents.
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USC vs. Purdue Matchup Info
- Game date: Saturday, September 13, 2025
- Game time: 3:30 p.m. ET
- Location: West Lafayette, Indiana
- Venue: Ross-Ade Stadium
- TV channel: CBS
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USC vs. Purdue Odds and Prediction
- Spread favorite: Trojans (-20.5)
- Moneyline: Trojans (-1538), Boilermakers (+862)
- Total: 59.5 points
- Pick ATS: Purdue (+20.5)
- Pick OU: Under (59.5)
- Prediction: USC 32, Purdue 25
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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USC vs. Purdue Betting Records and Insights
- USC has won two games against the spread this season.
- Purdue has covered once in two matchups with a spread this year.
- The Trojans have covered the spread when playing as at least 20.5-point favorites in two of two chances this season.
- So far this season, two USC games have gone over the point total.
- Purdue has yet to hit the over in any game this season.