In the game between the Denver Broncos and Indianapolis Colts on Sunday, Sept. 14 at 4:05 p.m. ET, our projection model expects the Broncos to emerge victorious. Seeking projections on the final score, spread, and point total, too? Find a complete game projection below.
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Broncos vs. Colts Game Info and TV Channel
- When: Sunday, September 14, 2025 at 4:05 p.m. ET
- Where: Lucas Oil Stadium in Indianapolis, Indiana
- TV: CBS
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
- Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Listen to the game on KOA 850 AM & 94.1 FM
Broncos vs. Colts Odds and Betting Info
- Spread favorite: Broncos (-2.5)
- Moneyline: Broncos (-123), Colts (+103)
- Total: 43.5 points
Broncos vs. Colts Prediction
- Pick ATS: Broncos (-2.5)
- Pick OU: Over (43.5)
Prediction:
Broncos 27 - Colts 18
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Broncos vs. Colts Betting Insights (2024 Stats)
- The Broncos compiled a 12-5-0 record against the spread last season.
- The Colts won nine games against the spread last year, while failing to cover eight times.
- Denver was favored by 2.5 points or more seven times last season, and covered the spread in each of those games.
- Indianapolis was an underdog by 2.5 points or more 10 times last year, and covered the spread in six of those contests.
- Last season, 11 of the Broncos' games went over the point total.
- Colts games went over the point total 10 out of 17 times last season.
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